Introduction: One approach to reducing stress and increasing quality of life among college students is teaching self-compassion. The goal of this study was to conduct the first pilot evaluation among college students of the Making Friends with Yourself self-compassion intervention. Method: Twenty-five students participated in the eight-week intervention. Students also participated in focus groups after the intervention ended and completed pre and post measures of psychosocial outcomes. Results: The intervention was found to be feasible and acceptable. On average, students attended six of the eight sessions, ranging from two to eight sessions. Focus group data revealed that students found the intervention to be acceptable. Finally, students reported significantly increased mindfulness and self-compassion and significantly decreased stress and academic stress after the intervention. Discussion: An intervention designed to increase college-students’ self-compassion may be feasible and acceptable.